1) Postdoctoral position in Cancer Epigenetics/Immunobiology

The Micevic Lab is currently seeking a highly motivated postdoctoral researcher with a strong interest and experience in the fields of T-cell biology, immunology, and epigenetics. The group is broadly interested in cancer immunology with specific interests in identifying epigenetic mechanisms regulating CD8 T cell memory formation and exhaustion. Using mouse models, single cell approaches (scRNA-Seq, ATACseq), genetic perturbation tools (CRISPR) and clinical tissues samples, the group aims to lay the foundation for the next-generation of cancer immunotherapies. The position is based in New Haven, CT at Yale University, one of the world's leading locations for life sciences. Relevant background: https://www.pnas.org/doi/abs/10.1073/pnas.2304319120

Your profile

Required

• Ph.D. in Molecular Biology/ Biochemistry, Immunology, Cancer immunobiology, genetics or related fields.
• Demonstrated expertise (peer-reviewed publications) in the fields of immunology, cancer biology and/or epigenetics.
• Experience in immunology techniques (flow cytometry, T-cell based assays, ELISA).
• Proficient with molecular biology techniques (cell culture, RNA extraction etc. ).
• Fluency in English, excellent written and communication skills.

Preferred

• Experience with single cell experiments, epigenetic techniques (ATAC-Seq, ChIP-Seq) is considered a plus.
• Expertise using CRISPR-based approaches.
• Trained for mouse work (handling, injections, tissue harvest).

Your position

• Planning, designing, and executing experiments.
• Analyzing, structuring, and presenting data.
• Participating in and developing collaborative projects with Ph.D. students and staff scientists.
• Preparation of scientific reports, meetings, journal articles and funding applications.
• Communicating science at local and international meetings.
• Participating in common lab tasks.
• Opportunities for mentoring PhD students.

Please send your CV, a cover letter and names of three references to Dr. Goran Micevic (goran.micevic at yale.edu) with subject line "Micevic Lab" by Sep 1.

2) Postdoctoral position in Computational Biology

We apply high-throughput single-cell multi-omics profiling (e.g., scRNA-seq, TCR-Seq, ATAC-seq, Methyl-Seq) to help decipher the cell signaling, epigenetic/transcriptomic regulation that is important for cancer immunology, as well as develop T cell-based cancer immune therapies.

Required

• Ph.D. in Computational Biology, Bioinformatics or related life sciences field.
• Demonstrated expertise (peer-reviewed publications) in analyzing single-cell and/or spatial transcriptomic datasets.
• Experience with UNIX/Linux command line, high performance computational cluster use.
• Fluency in English, excellent written and communication skills.

Your position 

• Planning and helping design single-cell and/or spatial transcriptomic experiments (scRNA-Seq, ATAC-Seq, CUT&RUN, TCR-Seq, ChIP-Seq, CosMx).
• Analyzing transcriptional, epigenetic and spatial data.
• Participating in and developing collaborative projects with postdocs and Ph.D. students.
• Preparation of scientific reports, meetings, journal articles and funding applications.
• Communicating science at local and international meetings.
• Participating in common lab tasks.
• Opportunities for mentoring PhD students.

Please send your CV, a cover letter and names of three references to Dr. Goran Micevic (goran.micevic at yale.edu) with subject line "Micevic Lab-Computational" by Sep 1.